Bart Nelissen
Phosphate Selective Polymers

Project Overview

My project in the Smith group involved the synthesis of novel phosphate binding polymers with biomedical applications. This research was supported by The Wellcome Trust, and unfortunately I am unable to give many details of the project, as we are seeking patent protection for the systems we developed. The project involved the synthesis of novel phosphate binding systems – which show the highest affinity of any receptors ever reported for inorganic phosphate anions. The binding process was investigated using a variety of techniques – including NMR, fluorescence and potentiometry. It is hoped that these systems will, in the future, give rise to novel materials with real medicinal applications.

Destination – Researcher (Drug Optimisation) at Astra Zeneca (Loughbrough)

After one year at Astra Zeneca, I have now returned to Dave's group to continue commercial development of our phosphate binding system. Research which currently has patent pending and which is attracting commercial interest.

I have also recently been awarded a BYEF grant by the Yorkshire regional development agency (£30000) which is enabling me to develop related technology with potential biomedical commercial applications.

International conferences attended - Bio 2005 (Washington, USA) and Bio 2006 (Chicago, USA)