It is suggested that a certain drug, given to children to prevent motion sickness, may predispose them to schizophrenia in later life. To test this hypothesis, 200 children were identified from medical records as having received the drug regularly. Attempts were made to trace these individuals (now aged between 25 and 30) and all but twelve were found. A control group of 200 who were known not to have used the drug was selected and matched to the first group in socioeconomic status. Of this group 15 could not be traced. The number of individuals in each group showing schizophrenic symptoms was recorded.