Prof David K. Smith

Photo of David K. Smith

Group Leader

Dave was promoted to a Professorship in July 2006

Jan 1999-Present: Department of Chemistry, University of York

Promoted to Senior Lecturer, October 2004.
Promoted to Professor, July 2006.

Jan 1997-Dec 1998: Royal Society European Post Doctoral Research Fellowship

With Professor Francois Diederich - ETH Zurich

Oct 1993-Dec 1996: PhD, University of Oxford

Supervisor: Professor Paul Beer

Oct 1989-Jun 1992: BA (Hons) First Class, University of Oxford

Awarded Proximae Accessit for outstanding finals performance
Postmaster scholar

Research Track Record in Figures (as of November 2011)

>100 peer-reviewed papers in career
>90 independent peer-reviewed papers since 1999
Many papers in the highest-quality journals
2 Patents
Encyclopedia Volume Editor
1 book and 1 book chapter
2 Encyclopedia chapters
>4000 citations - average >35 citations per paper
H Index = 37 (according to Thomson ISI)
Major funders EPSRC, ERC, The Wellcome Trust, The Leverhulme Trust and Polymer/Formulation Industry

Research Awards

Corday Morgan Award in 2012 from The Royal Soceity of Chemistry for contributions to nanoscience.
Awarded the Bob Hay Lectureship in 2011 for contributions to supramolecular science.

Current Research Summary

My research focuses on supramolecular/nanoscale chemistry, forming the basis of a distinctive, thriving research team. We are interested in research at interfaces between chemistry, biology and physics.

Supramolecular dendrimers – we have developed new switchable and controllable soft materials – research which has formed the basis of numerous lectures at international conferences as well as publications in leading chemical journals (e.g. J. Am. Chem. Soc. 2003, 125, 9010, J. Am. Chem. Soc. 2008, 130, 9113). These soft matter systems have potential applications in the development of modified nanoscale materials (Chem. Commun. 2008, 4601, Langmuir 2009, 25, 8786). In recent work, we have been developing an understanding of how complex mixtures can spontaneously self-assemble (Chem. Commun. 2009, 316, Chem. Eur. J. 2009, 15, 372), as well as developing soft materials with potential applications in tissue engineering (Angew. Chem. 2008, 47, 8002)

Biological targets – we have used our expertise in binding biological targets to develop materials with potential applications in gene therapy. This has led to high impact publications and forms the basis of much of my outreach lecturing (e.g. Angew. Chem. Int. Ed. 2005, 44, 2556, Angew. Chem. Int. Ed. 2009, 48, 4047, J. Am. Chem. Soc. 2011, 133, 20288). We work extensively with modellers to provide unique insight into the behaviour of these nanoscale systems (J. Am. Chem. Soc. 2009, 131, 9686, Chem. Sci. 2010, 1, 393). We are also developing dendritic polymers which bind to other key biological targets such as heparin - which has applications in post-surgical intervention (Angew. Chem. Int. Ed. 2011, 50, 4675).

Medicinal polymers – we are generating polymers with the ability to intervene in various diseases – including hyperphosphatemia. We are also developing materials designed to reduce cholesterol levels. We have recently applied for patent protection in this area (UK Patent P110446GB).

Key Invited Lectures

I have given invited lectures at a number of international conferences – including ACS (New York, 2002), International Dendrimer Symposium (Berlin 2002, Michigan 2004). I have also been an invited lecturer in Strasbourg (2005), have made a lecture tour of the USA (2005) and was an visiting professor in Hong Kong/China (2006). I have also participated in a joint UK/India meeting in Delhi (2007) as well as delivered a lecture at the International Dendrimer Symposium in Toulouse and been an invited keynote speaker at meetings in Zagreb (Croatia), Athens (Greece), Copenhagen (Denmark) and Lodz (Poland). In 2010, I was invited lecturer at the ACS meeting in Boston, and gave three plenary lectures across China, supported by the RSC and Unilever. In 2011, I gave plenary lectures at international conferences in Brighton (ISMSC) and Liverpool (Nanoscale Chirality) and further invited lectures at the ACS meeting in Denver. I regularly particpate in interdisciplinary science meetings (e.g. Japan, Royal Society, 2008)

Education Awards

Royal Society of Chemistry Higher Education Award 2004. National award (two awarded annually). Citation: ‘Distinguished as a lecturer with great commitment and enthusiasm whose teaching skills and innovation in the lecture and laboratory have had a notable impact on the success of undergraduates and the motivation of schoolteachers and their students’.

Vice Chancellor’s teaching prize (2006) and Department of Chemistry Teaching Prize (2002) for innovative approach to undergraduate teaching and excellent undergraduate feedback. I am currently Chair of Teaching in the Chemistry Department at York

Schools Lecturing/Popularisation of Science

I have developed a 40-50 minute demonstration lecture 'Medicine Beyond the Molecule', delivered to over twenty five thousand 16-18 year olds. This lecture aims to popularise chemistry, emphasising the connections between chemistry and medicine and the important role played by chemists in drug discovery. I have recently also developed a new demonstration lecture: 'Marvellous Molecular Nanomaterials' which emphasises the key role played by chemists.

I have developed a YouTube channel (http://www.youtube.com/professordaveatyork) to popularise organic chemistry, which has so far received well over 200,000 video views, as well as generating hundreds of comments and having hundreds of subscribers.

Editing/Esteem

I was responsible for all editorial aspects of two ‘special issue’ of Tetrahedron - Recent Developments in Dendrimer Chemistry (Tetrahedron, 2003, 59, 3787-4024) and Low Molecular Weight Organic Gelators (Tetrahedron, 2007, 63, 7271-7494). My role included commissioning papers from researchers worldwide, organising the refereeing process, making senior editorial decisions about the acceptability of submitted papers and editing. I am an editorial board member of Education in Chemistry, Tetrahedron and Chemistry (A Central Journal). I edited the 'Soft Matter' volume of the Encyclopedia: Supramolecular Chemistry: From Molecules to Nanomaterials, published by Wiley.

I was a symposium organiser at the pan-European general chemistry conference, EUCheMS 2, attended by >2000 people in Turin, Italy (2008), and was on the organising committee of the International Supramolecular and Macrocyclic Conference in Brighton (July 2011).
I am Vice Chair of the European COST Network TD0802 on Biomedical Applications of Dendrimers (Mar 2009 - Mar 2013)