A graph with two panels. Each panel shows the creatinine measured at each of four times for each patient separately as line joining four points. The horizontal axis is labeled "Months" with times marked as –6, 0, 3, and 6. These times are shown equally spaced rather than given their numerical value. The vertical axis is labeled "Creatinine (micromoles per litre)" and numbered 50, 100, 150, 200, 250, and 300.

The first panel shows group A. At time –6 the range of creatinine is 100 to 220. At time 0 the range is 120 to 300 and some lines from time –6 to time 0 slope upwards, some slope downwards. At time 3 the range is 90 to 300 and most of the lines from time 0 to time 3 slope downwards. At time 6 the range is 55 to 200 and most of the lines from time 3 to time 6 slope downwards. A P value is shown connecting times –6 and 6: P = 0.003. A P value is shown connecting times 0 and 6: P = 0.001.

The second panel shows group B. At time –6 the range of creatinine is 90 to 190. At time 0 the range is 120 to 210 and some lines from time –6 to time 0 slope upwards, some slope downwards. At time 3 the range is 90 to 200 and some of the lines from time 0 to time 3 slope upwards, some slope downwards. At time 6 the range is 100 to 180 and some of the lines from time 3 to time 6 slope upwards, some slope downwards. A P value is shown connecting times –6 and 6: P = 0.514. A P value is shown connecting times 0 and 6: P = 0.440.

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Last updated: 27 July, 2009.