Randomised Trial of Calcium and Vitamin D supplementation in Primary Care (Funder - Northern and Yorkshire, R&D);
This project is based in primary care and more than 3,000 women aged 70 years and over have been randomised to receive calcium and vitamin D supplements for act as controls to see if this reduces fractures.  Study results published by the BMJ (no benefit of supplements).

· Randomised Trial of Calcium with or without Vitamin D (RECORD trial) for secondary fracture prevention (Funder - MRC);
This is a secondary prevention trial using calcium or vitamin D for fracture prevention.  Study results published by the Lancet (no benefit of supplements).

· Randomised Trial of treatments for backpain (UKBEAM) (Funder - MRC);
Factorial trial looking at the value of manipulation, exercise or best care for acute backpain.  Study results published by the British Medical Journal November 2004.  Manipulation produced modest effects and was cost effective.

· Randomised Trial of physiotherapy for neck pain (SPRINTER with Hull University) (Funder - Northern and Yorkshire R&D);
Fully randomised patient preference trial looking at a brief intervention for neck pain.  Study results published by the British Medical Journal January 2005.  Usual care produced better effects and showed an interaction with patient preference.

· Randomised Trial of physiotherapy for back pain (Funder - ARC with Manchester);

Trial published:

Johnson RE, Jones GT, Wiles NJ, Chaddock C, Potter RG, Roberts C, Symmons DPM, Watson PJ, Torgerson DJ, MacFarlane GJ. Active exercise, education and cognitive behavioural therapy for persistent disabling low back pain. Spine 2007;32:1578-85.

· Randomised Trial of Laparoscopic Colposuspension (COLPO with Manchester University) (Funder - MRC);
Fully randomised patient preference trial.  Study published by British Journal of Obstetrics and Gynaecology.

· Randomised Trial of larval therapy for venous ulcers (Funder - NHS HTA);
Trial of larval therapy currently undergoing recruitment.  Further details from Jo Dumville (jd34@york.ac.uk)

· Randomised Trial of ultrasound therapy for venous ulcers (Funder - NHS HTA);
Trial recruiting. Further details Jude Watson (jmw19@york.ac.uk)

· Randomised Trial of mattresses for pressure sores (Funder - NHS HTA);
Trial published by BMJ.

· Randomised Trial of computer software to improve literacy among school children (Funder – Sheffield University);
Largest RCT of computer software for improving literacy to date.  Trial completed and published no benefit of computer software. Further details from Carole Torgerson cjt3@york.ac.uk

Randomised Trial of incentives for adult learners (Funder - Sheffield University).
Cluster randomised trial of using incentives to improve attendance and increase literacy outcomes.  Further details from Carole Torgerson cjt3@york.ac.uk

Trial completed – incentives reduce attendance to adult literacy classes.

Randomised trial of cyrotherapy versus self-treatment with salicylic acid (EVERT Trial ) (Funder – NHS HTA programme)

Trial in recruitment phase. Further details - Sarah Cockayne (esc5@york.ac.uk)

Randomised controlled trial of yoga therapy for low back pain (Funder – Arthritis and Rheumatism Council)

Fully randomised patient preference trial. Trial recruiting (01/04/2007) – Helen Cox (hc18@york.ac.uk) or Helen Tilbrook (het2@york.ac.uk)