Research Publications

Click here for a list of Dave Smith's Presentations

To see full up-to-date citation counts for all papers and to check Dave's h-index, please use this link to Dave's Google Scholar Profile


Number Reference
174 V.M.P. Vieira, E. Laurini, P. Posocco, S. Pricl, V. Liljestrom, M.A. Kostiainen, D.K. Smith*
Self-assembled multivalent (SAMul) heparin binders – structure-activity relationships and characterization of the electrostatically-bound hierarchical nanoscale aggregates
Manuscript in preparation.
173 A.M. Steer, N. Bia, D.K. Smith, P.A. Clarke*
Title to be announced later
Manuscript submitted.
172 C.W. Chan, D.K. Smith*
Effect of Buffer on Heparin Binding and Sensing in Competitive Aqueous Media
Supramol. Chem. in press.
171 C.W. Chan, E. Laurini, P. Posocco, S. Pricl, D.K. Smith*
Chiral recognition at self-assembled multivalent (SAMul) nanoscale interfaces–enantioselectivity in polyanion binding
Chem. Commun. 2016, 52, 10540-10543.
170 B.O. Okesola, D.K. Smith*
Applying low-molecular weight supramolecular gelators in an environmental setting–self-assembled gels as smart materials for pollutant removal
Chem. Soc. Rev. 2016, 45, 4226-4251
169 D.K. Smith*
Programmed Design of Skilful Chemists
Education in Chemistry, 2016, 53 (4), 18-21
168 L.E. Fechner, B. Albanyan, V.M.P. Vieira, E. Laurini, P. Posocco, S. Pricl D.K. Smith*
Electrostatic binding of polyanions using self-assembled multivalent (SAMul) ligand displays–structure–activity effects on DNA/heparin binding
Chem. Sci. 2016, 7, 4653-4659.
167 V.E. Gewin
Turning Point: Out for Chemistry (Interview with Nature)
Nature, 2016, 531, 265.
166 C.W. Chan, D.K. Smith*
Pyrene-Based Heparin Sensors in Competitive Aqueous Media – The Role of Self-Assembled Multivalency (SAMul)
Chem. Commun. 2016, 52, 3785-3788.
165 B.O. Okesola, S.K. Suravaram, A. Parkin, D.K. Smith*
Selective Extraction and In Situ Reduction of Precious Metal Salts from Model Waste to Generate Hybrid Gels with Embedded Electrocatalytic Nanoparticles
Angew. Chem. Int. Ed. 2016, 55, 183-187.
164 D.J. Cornwell, O.J. Daubney, D.K. Smith
Photopatterned Multidomain Gels: Multi-Component Self-Assembled Hydrogels Based on Partially Self-Sorting 1,3:2,4-Dibenzylidene-D-sorbitol Derivatives
J. Am. Chem. Soc., 2015, 137, 15486-15492.
163 G. Ionita, A.M. Ariciu, D.K. Smith, V. Chechik*
Ion Exchange in Alginate Gels - Dynamic Behaviour Revealed by Electron Paramagnetic Resonance
Soft Matter, 2015, 11, 8968-8974.
162 A.M. Caminade, D. Yan, D.K. Smith
Self-assembled sorbitol-derived supramolecular hydrogels for the controlled encapsulation and release of active pharmaceutical ingredients
Chem. Soc. Rev, 2015, 44, 3870-3873.
161 J. Buendia, E. Matesanz, D.K. Smith, L. Sanchez,
Multi-Component Supramolecular Gels for the Controlled Crystallization of Drugs: Synergistic and Antagonistic Effects
Cryst. Eng. Comm., 2015, 17, 8146-8152.
160 E.J. Howe, B.O. Okesola, D.K. Smith*
Self-assembled sorbitol-derived supramolecular hydrogels for the controlled encapsulation and release of active pharmaceutical ingredients
Chem. Commun., 2015, 51, 7451-7454.
159 B.O. Okesola, V.M.P. Vieira, D.J. Cornwell, N.K. Whitelaw, D.K. Smith*
1,3:2,4-Dibenzylidene-D-sorbitol (DBS) and its derivatives - Efficient, versatile and industrially-relevant low-molecular-weight gelators with over 100 years of history and a bright future
Soft Matter, 2015, 11, 4768-4787.
158 S.M. Bromfield, D.K. Smith*
Heparin versus DNA – Chiral Preferences in Polyanion Binding to Self-Assembled Multivalent (SAMul) Nanostructures
J. Am. Chem. Soc. 2015, 137, 10056-10059
157 D.J. Cornwell, D.K. Smith*
Expanding the Scope of Gels – Combining Polymers with Low-Molecular-Weight Gelators to Yield Modified Self-Assembling Smart Materials with High-Tech Applications
Mater. Horiz. 2015, 2, 279-293.
156 S. Rohner, J. Ruiz-Olles, D.K. Smith*
Speed versus stability – structure-activity effects on the assembly of two-component gels
RSC Adv. 2015, 5, 27190-27196.
155 D.K. Smith*
What do We Want Our Students to Be?
Education in Chemistry, 2014, Novembver, Endpoint.
154 D.J. Cornwell, D.K. Smith*
Multi-Domain Hybrid Hydrogels – Spatially-Resolved Photo-Patterned Synthetic Nanomaterials Combining Polymer and Low-Molecular-Weight Gelators
Angew. Chem. Int. Ed. 2014, 53, 12461-12465.
153 A. Caragheorgheopol, W. Edwards, J.G. Hardy, D.K. Smith, V. Chechik*
Using EPR as a Unique Probe of Molecular-Scale Mobility and Solvation in Nanostructured Self-Assembled Gel-Phase Materials
Langmuir, 2014, 30, 9210-9218.
152 S.M. Bromfield, P. Posocco, M. Fermeglia, J. Tolosa, A. Herreros-Lopez, S. Pricl,* J. Rordiguez-Lopez,* D.K. Smith*
Shape-Persistent and Adaptive Multivalency – Rigid Transgeden (TGD) and Flexible PAMAM Dendrimers for Heparin Binding
Chem. Eur. J. 2014, 20, 9666-9674.
151 D.K. Smith*
'No Sexuality Please We're Scientists'
Chemistry World. 2014, April.
150 W. Edwards, D.K. Smith*
Enantioselective Component Selection in Multi-Component Supramolecular Gels
J. Am. Chem. Soc. 2014, 136, 1116-1124.
149 D.K. Smith*
iTube, YouTube, WeTube - Social Media Videos in Chemistry Education and Outreach
J. Chem. Educ. 2014, 91, 1594-1599.
148 S.M. Bromfield, P. Posocco, C.W. Chan, M. Calderon, S. Guimond, J.E. Turnbull, S. Pricl, D.K. Smith*
Nanoscale Self-Assembled Multivalent (SAMul) Heparin Binders in Highly Competitive, Biologically Relevant, Aqueous Media
Chem. Sci. 2014, 5, 1484-1492.
This paper has been the subject of a YouTube video to explain the content to the general public.
This paper was also featured in Chemistry World magazine
147 A. Tschiche, A.M. Staedtler, S. Malhotra, H. Bauer, C. Böttcher, S. Sharbati, M. Calderón, M. Koch, T.M. Zollner, A. Barnard, D.K. Smith, R. Einspanier, N. Schmidt,* R. Haag*
Polyglycerol-Based Amphiphilic Dendrons as Potential siRNA Carriers for In Vivo Applications
J. Mater. Chem. B., 2014, 2, 2153-2167.
146 A. Barnard, P. Posocco, M. Fermeglia, A. Tschiche, M. Calderon, S. Pricl, D.K. Smith*
Double-Degradable Responsive Self-Assembled Multivalent Arrays – Temporary Nanoscale Recognition between Dendrons and DNA
Org. Biomol. Chem. 2014, 12, 446-455.
145 B.O. Okesola, D.K. Smith,*
Versatile Supramolecular pH-Tolerant Hydrogels which Demonstrate pH-Dependent Selective Adsorption of Dyes from Aqueous Solution
Chem. Commun. 2013, 49, 11164-11166.
144 S.M. Bromfield, E. Wilde, D.K. Smith,*
Heparin Sensing and Binding – Taking Supramolecular Chemistry Towards Clinical Applications
Chem. Soc. Rev. 2013, 42, 9184-9195.
143 D. Cornwell, B.O. Okesola, D.K. Smith*
Hybrid Polymer and Low Molecular Weight Gels – Dynamic Two-Component Soft Materials with Both Responsive and Robust Nanoscale Networks
Soft Matter, 2013, 9, 8730-8736.
This article was featured by chemistry world - 'Responsive Gel Stays Strong'
142 W. Edwards, D.K. Smith*
Dynamic Evolving Two-Component Supramolecular Gels – Hierarchical Control over Component Selection in Complex Mixtures
J. Am. Chem. Soc, 2013, 135, 5911-5920.
This article was recommended by David Lynn at Faculty of 1000 as 'New Finding, Technical Advance, Good for Teaching' (link requires subscription)
141 S.M. Bromfield, P. Posocco, M. Fermeglia, S. Pricl, J. Rodriguez-Lopez, D.K. Smith*
A Simple New Competition Assay for Heparin Binding in Serum Applied to Multivalent PAMAM Dendrimers
Chem. Commun. 2013, 49, 4830-4832.
140 D.J. Welsh, P. Posocco, S. Pricl, D.K. Smith*
Self-Assembled Multivalent RGD-Peptide Arrays – Morphological Control of Integrin Binding
Org. Biomol. Chem. 2013, 11, 3177-3186.
139 S.M. Bromfield, A. Barnard, P. Posocco, M. Fermeglia, S. Pricl, D.K. Smith*
Mallard Blue - A High-Affinity Selective Heparin Sensor which Operates in Highly-Competitive Media
J. Am. Chem. Soc. 2013, 135, 2911-2914.
138 G. Ionita, G. Matinescu, C. Ilie, F.D. Anghel, D.K. Smith, V. Chechik
Sorption of Metals by Poly(ethylene glycol)/-beta-CD Hydrogels Leads to Gel-Embedded Metal Nanoparticles
Langmuir, 2013, 29, 9173-9178.
137 M.M. Smith, W. Edwards D.K. Smith*
Self-Organisation Effects in Nanoscale Gels Self-Assembled from Simple Mixtures of Commercially Available Molecular-Scale Components
Chemical Science, 2013, 4, 671-676.
136
V.J. Nebot, D.K. Smith
Techniques for the Characterisation of Molecular Gels
Functional Molecular Gels, Ed. B. Escuder, J.F. Miravet, RSC Publishing, 2014, pp 30-66.
135 P. Posocco, E. Laurini, V. dal Col, D. Marson, L. Peng, D.K. Smith, B. Klajnert, M. Bryszewska, A.M. Caminade, J.P. Majoral, M. Fermeglia, K. Karatasos, S. Pricl
Multiscale Modelling of Dendrimers and Dendrons for Drug and Nucleic Acid Delivery
Dendrimers in Biomedical Applications, Ed. L. Peng, B. Klajnert, V. Cena, RSC Publishing, 2013.
134 M.F. Ottaviani, D. Appelhans, F.J. de la Mata, S. Garcia-Gallego, A. Fattori, C. Coppola, M. Cangiotti, L. Fiorani, J.P. Majoral, A.M. Caminade, M. Bryszewska, D.K. Smith, N. Garti, B. Klajnert
Characterisation of Dendrimers and their Ineractions with Biomolecules by Means of Electron Magnetic Resonance
Dendrimers in Biomedical Applications, Ed. L. Peng, B. Klajnert, V. Cena, RSC Publishing, 2013.
133 S. Pricl, D.K. Smith*
From Multivalent Dendrons to Self-Assembled Multivalent Dendrimers – A Combined Experimental and Theoretical Approach
Dendrimers in Biomedical Applications, Ed. L. Peng, B. Klajnert, V. Cena, RSC Publishing, 2013.
132 A. Barnard, A. Tschiche, M. Calderon, R. Haag, D.K. Smith*
Investigating the Effects of a PEG Additive on the Biomolecular Interactions of Self-Assembled Hybrid Nanoscale Architectures
Org. Biomol. Chem. 2012, 10, 8403-8409.
131 A.J. Thompson, J. Dabin, J. Iglesias-Fernandez, A. Ardevol, Z. Dinev, S.J. Williams, A. Siriwardena, C. Moreland, T.-C. Hu, D.K. Smith, H.J. Gilbert, C. Rovira*, G.J. Davies*
The Reaction Coordinate of a Bacterial GH47 Alpha-Mannosidase: A Combined Quantum Mechanical and Structural Approach
Angew. Chem. Int. Ed. 2012, 51, 10997-11001.
130 E. Dux, D.K. Smith
Curried Chemistry
Chemistry Review, 2011, 22, Nov, 26-30.
129 C.A. Lagadec, D.K. Smith*
Structure-Activity Effects in Peptide Self-Assembly and Gelation – Dendritic versus Linear Architectures
Chem. Commun. 2012, 48, 7817-7819.
128 A. Barnard, D.K. Smith*
Self-Assembled Multivalency - Dynamic Ligand Arrays for High-Affinity Binding
Angew. Chem. Int. Ed. 2012, 51, 6572-6581.
127 D.K. Smith
Tiny Technology (Two Book Reviews)
Chemistry World 2012, May, 63.
126 D.K. Smith
Designing Dendrimers (Book Review)
Angew. Chem. Int. Ed. 2012, 51, 6045-6046.
125 J.G. Hardy, A.R. Hirst, D.K. Smith*
Exploring Molecular Recognition Pathways in One- and Two-Component Gels Formed by Dendritic Lysine-Based Gelators
Soft Matter 2012, 8, 3399-3406
124 W. Edwards, D.K. Smith*
Cation-Selective Silver-Responsive Organogel - Exploiting Silver-Alkene Interactions in the Gel-Phase
Chem. Commun. 2012, 48, 2767-2769.
123 M.F. Ottaviani, M. Cangiotti, L. Fiorani, A. Barnard, S.P. Jones, D.K. Smith*
Probing dendron structure and nanoscale self-assembly using computer-aided analysis of EPR spectra
New J. Chem. 2012, 36, 469-476 (invited article for special issue on dendrimer chemistry).
122 A. Barnard, P. Posocco, S. Pricl, M. Calderon, R. Haag, M.E. Hwang, V.T. Shum, D.W. Pack, D.K. Smith*
Degradable Self-Assembling Dendrons for Gene Delivery – Experimental and Theoretical Insights into the Barriers to Cellular Uptake
J. Am. Chem. Soc. 2011, 133, 20288-20300.
121 D.K. Smith*
Soft Matter Science - A Supramolecular Perspective
Supramolecular Chemistry: From Molecules to Nanomaterials, Eds. P.A. Gale, J.W. Steed, Volume 7, pp 3169-3182, Wiley-VCH, 2012.
120 D.K. Smith*
Self-Assembling Fibrillar Networks
Supramolecular Chemistry: From Molecules to Nanomaterials, Eds. P.A. Gale, J.W. Steed, Volume 7, pp 3355-3376, Wiley-VCH, 2012.
119 J.R. Moffat, D.K. Smith*
Fluorescent ‘two-faced’ polymer wafers with embedded pyrene-functionalised gelator nanofibres
Chem.Commun. 2011, 47, 11864-11866.
118 D.K. Smith*
Comments on Nature Paper (Mixed aromatic–aliphatic organic nanoparticles as carriers of unidentified infrared emission features, by S. Kwok and Y. Zhang)
Nature 2011, online comments
These comments played an important role in correcting major errors in this Nature publication
117 W. Fischer, M.A. Quadir, A. Barnard, D.K. Smith, R. Haag*
Controlled Release of DNA from Photoresponsive Hyperbranched Polyglycerols with Oligoamine Shells
Macromol. Bioscience 2011, 11, 1736-1746
116 D.K. Smith*
From Crazy Chemists to Engaged Learners through Education
Nature Chemistry 2011, 3, 681-684.
This article has generated some debate and further commentary - click here to see the debate.
115 M. Smith, D.K. Smith*
Self-Sorting Multi-Gelator Gels – Mixing and Ageing Effects in Thermally Addressable Supramolecular Soft Nanomaterials
Soft Matter 2011, 7, 4856-4860.
114 D.J. Welsh, D.K. Smith*
Comparing Dendritic and Self-Assembly Strategies to Multivalency – RGD Peptide-Integrin Interactions
Org. Biomol. Chem. 2011, 9, 4795-4801
Highlighted as a Hot Article
113 A.C. Rodrigo, A. Barnard, J. Cooper, D.K. Smith*
Self-Assembling Ligands for Nanoscale Multivalent Heparin Binding
Angew. Chem. Int. Ed. 2011, 50, 4675-4679.
112 S.P. Jones, N.P. Gabrielson, C.-H. Wong, H.-F. Chow, D. W. Pack, P. Posocco, M. Fermeglia, S. Pricl, D.K. Smith*
Hydrophobically Modified DNA Binding Dendrons – Developing Structure-Activity Relationships for DNA Binding and Gene Transfection
Mol. Pharm. 2011, 8, 416-429.
111 W. Edwards, C. Lagadec, D.K. Smith*
Solvent-Gelator Interactions - Using Empirical Solvent Parameters to Better Understand the Self-Assembly of Gel-Phase Materials
Soft Matter 2011, 7, 110-117.
110 C. Lagadec, D.K. Smith*
Synthetically Accessible, Tunable, Low-Molecular-Weight Oligopeptide Organogelators
Chem. Commun. 2011, 47, 340-342.
109 I.A. Coates, D.K. Smith*
Hierarchical Assembly - Dynamic Gel-Nanoparticle Hybrid Soft Materials Based on Biologically Derived BUilding Blocks
J. Mater. Chem. 2010, 20, 6696-6702.
108 P. Posocco, S. Pricl*, S.P. Jones, A. Barnard, D.K. Smith*
Less is More - Multiscale Modelling of Self-Assembling Multivalency and its Impact on DNA Binding and Gene Delivery
Chem. Sci. 2010, 1, 393-404.
107 D.K. Smith*
Highly Tunable Modular Dendrons for DNA Binding and Delivery
PMSE Preprints, 2010.
106 S.P. Jones, G.M. Pavan*, A. Danani, S. Pricl, D.K. Smith*
Quantifying the Effect of Surface Ligands on Dendron-DNA Interactions - New Insights into Multivalency through a Combined Experimental and Theoretical Approach
Chem. Eur. J. 2010, 16, 4519-4532.
105 D.K. Smith*
Supramolecular Gels - Building Bridges
Nature Chem. 2010, 2, 162-163.
Commentary on exciting work by Aida and co-workers
104 X. Zhang, V. Chechik, D.K. Smith, P.H. Walton, A.-K. Duhme-Klair, Y. Luo
Nanocomposite Hydrogels - Controlled Synthesis of Chiral Polyaniline Nanofibers and their Inclusion in Agarose
Synth. Metals 2009, 159, 2135-2140.
103 G.M. Pavan, A. Danani, S. Pricl, D.K. Smith*
Modeling the Multivalent Recognition between Dendritic Molecules and DNA - Understanding How Ligand Sacrifice and Shielding may Enhance Binding
J. Am. Chem. Soc. 2009, 131, 9686-9694.
102 K.J. Winstanley, S.J. Allen, D.K. Smith*
Encapsulated Binding Sites – Synthetically Simple Receptors for the Binding and Transport of HCl
Chem. Commun. 2009, 4299-4301.
101 I.A. Coates, D.K. Smith*
Controlled Self-Assembly - Synthetic Tunability and Covalent Capture of Nanoscale Gel Morphologies
Chem. Eur. J. 2009, 15, 6340-6344.
100 D.J. Welsh, S.P. Jones, D.K. Smith*
On-Off Multivalent Recognition - Degradable Dendrons for Temprorary High-Affinity DNA Binding
Angew. Chem. Int. Ed. 2009, 48, 4047-4051.
99 J.R. Moffat, I.A. Coates, F.J. Leng, D.K. Smith*
Metathesis within Self-Assembled Gels – Transcribing Nanostructured Soft Materials into a More Robust Form
Langmuir (special issue on gels) 2009, 25, 8786-8793.
98 J.G. Hardy, C.S. Love, N.P. Gabrielson, D.W. Pack, D.K. Smith*
Synergistic Effects on Gene Delivery by Co-Formulation of Dendritic Polycations with Lipofectamine 2000
Org. Biomol. Chem. 2009, 7, 789-793.
97 J.R. Moffat, D.K. Smith*
Controlled Self-Sorting in the Assembly of ‘Multi-Gelator’ Gels
Chem. Commun. 2009, 316-318.
96 D.K. Smith*
Lost in Translation? Chirality Effects in the Self-Assembly of Nanostructured Gel-Phase Materials
Chem. Soc. Rev. 2009, 38, 684-694.
This tutorial review provides an easy to read introduction to chirality in self-assembled gels.
95 A.R. Hirst, J.F. Miravet, B. Escuder, V. Castelletto, I.W. Hamley, D.K. Smith*
Self-Assembly of Two-Component Gels: Stoichiometric Control and Component Selection
Chem. Eur. J. 2009, 15, 372-379.
94 S.P. Jones, N.P. Gabrielson, D.W. Pack, D.K. Smith*
Synergistic Effects in Gene Delivery - A Structure-Activity Approach to the Optimisation of Hybrid Dendritic-Lipidic Transfection Agents
Chem. Commun. 2008, 4700-4702.
93 T.-C. Hu, J. Korczynska, D.K. Smith, M. Brzozowski*
High-molecular-weight polymers for protein crystallization: poly-gamma-Glutamic Acid based precipitants
Acta Cryst. D, 2008, D64, 957-963.
92 J.R. Moffat, G.J. Seeley, J.T. Carter, A. Burgess, D.K. Smith*
Nanostructured Polymers with Embedded Self-Assembled Reactive Gel Networks
Chem. Commun. 2008, 4601-4603.
91 A.R. Hirst, I.A. Coates, T. Boucheteau, J.F. Miravet,* B. Escuder, V. Castelletto, I.W. Hamley, D.K. Smith*
Low Molecular Weight Gelators - Elucidating the Principles of Gelation Based on Gelator Solubility and a Cooperative Binding Model
J. Am. Chem. Soc., 2008, 130, 9113-9121.
90 X. Zhang, V. Chechik, D.K. Smith, P.H. Walton, A.K. Duhme-Klair
Controlled Synthesis of Optically Active Polyaniline Nanorods and Nanostructured Gold Microspheres using Tetrachloroaurate as Efficient Oxidant of Aniline
Macromolecules, 2008, 41, 3417-3421.
89
A.R. Hirst, B. Escuder, J.F. Miravet, D.K. Smith
High-Tech Applications of Self-Assembling Supramolecular Nanostructured Gel-Phase Materials - From Regenerative Medicine to Electronic Devices
Angew. Chem. Int. Ed. 2008, 47, 8002-8018.
88 D.K. Smith*
Dendrimers and the Double Helix - From DNA Binding to Gene Therapy
Curr. Top. Med. Chem. 2008, 8, 1187-1203.
87 J.R. Moffat, D.K. Smith*
Metastable Two-Component Gel - Exploring the Gel-Crystal Interface
Chem. Commun. 2008, 2248-2250.
86 D.K. Smith*
From Nanochemisry to Nanomedicine - Delivering New Drugs
Education in Chemistry, 2008, 45, 113-116.
85

D.K. Smith
Molecular Gels - Nanostructured Soft Materials
Part of the book 'Organic Nanostructures', (eds. Atwood, Steed), 2008.
 This book chapter is designed to be a simple introduction to gels for people who have just started working in the area.
84 U. Hahn, A.R. Hirst, J.L. Delgado, A. Kaeser, B. Delavaux-Nicot, J.-F. Nierengarten*, D.K. Smith*
Hierarchical Self-assembly and Gelation of Organooxotin Structures Derived from Simple Building Blocks
Chem. Commun. 2007, 4943-4945.
83 M.A. Kostiainen*, G.R. Szilvay, J. Lehtinen, D.K. Smith*, M.B. Linder, A. Urtti, O. Ikkala
Precisely Defined Protein-Polymer Conjugates: Construction of Synthetic DNA Binding Domains on Proteins by Using Multivalent Dendrons
ACS Nano, 2007, 1, 103-113.
82 M.A. Kostiainen*, D.K. Smith*, O. Ikkala
Optically Triggered Release of DNA from Multivalent Dendrons by Degradation and Charge-Reversing Multivalency
Angew. Chem. Int. Ed. 2007, 46, 7600-7604.
81 H.F.M. Nelissen, D.K. Smith*
Synthetically Accessible High Affinity Phosphate Receptors
Chem. Commun., 2007, 3039-3041.
80 J. Korczynska, T.-C. Hu, D.K. Smith, J. Jenkins, R. Lewis, T. Edwards, A.M. Brzozowski
Microscale Vapour Diffusion for Protein Crystallization
Acta Cryst, 2007, D63, 1009-1015.
79 I.A. Coates, A.R. Hirst, D.K. Smith*,
Diverse Biomimetic Building Blocks for the Assembly of Gel-Phase Materials
J. Org. Chem., 2007, 72, 3937-3940.
78 C.S. Love, V. Chechik*, D.K. Smith*, I. Ashworth, C. Brennan
The Impact of Grubbs' Metathesis Cross-Linking on the Stability of Dendritic Nanoparticles
Langmuir, 2007, 23, 5787-5794.
77 K.J. Winstanley, D.K. Smith*
Ortho-Substituted Catechol Derivatives: The Effect of Intramolecular Hydrogen Bonding Pathways on Chloride Anion Recognition
J. Org. Chem. 2007, 72, 2803-2815.
76

D.K. Smith
Molecular Gels - Underpinning Nanomaterials with Organic Chemistry
Tetrahedron 2007, 63, 7283-7284.

75 J.G. Hardy, A.R. Hirst. I. Ashworth, C. Brennan, D.K. Smith*,
Exploring Molecular Recognition Pathways Within a Family of Gelators with Different Hydrogen Bonding Motifs
Tetrahedron (special issue), 2007, 63, 7397-7406.
74 J.G. Hardy, I. Ashworth, C. Brennan, D.K. Smith*,
Dendritic Receptors Designed to Bind Polyanions in Both Organic and Aqueous Media
Org. Biomol. Chem., 2007, 5, 900-906.
73 J.R. Moffat, G.J. Seeley, D.K. Smith*
Nanostructured Polymers with an Embedded Self-Assembled Gel-Phase Scaffold
Patent.
72

A.R. Hirst, B. Huang, V. Castelletto, I. W. Hamley, D.K. Smith*
Self-Organisation in the Assembly of Gels from Mixtures of Different Dendritic Peptide Building Blocks
Chem. Eur. J., 2007, 13, 2180-2188.

71 S.V. Brignell, D.K. Smith*
Crown Ether Functionalised Dendrons - Controlled Binding and Release of Dopamine in Both the Solution and Gel-Phase
New J. Chem (invited article, special issue), 2007, 31, 1243-1249.
70 D. Lam, B. Nelissen, D.K. Smith
Towards a Highly Selective Polymeric Phosphate Receptor
Polymer Preprints, 2006, 47, 203-204.
69 D.K. Smith*
Branching Out
Chemistry and Industry, 2006, 6 November, 30-31. (Essay Style Book Review)
68 D.K. Smith
Nanochemistry - Delivering New Medicines?
Chemistry Review, 2006, 16, September, 6-10.
67 D.K. Smith*
Dendritic Gels - Many Arms Make Light Work
Adv. Mater. 2006, 18, 2773-2778.
66 C.S. Love, I. Ashworth, C. Brennan, V. Chechik*, D.K. Smith*
Dendritic Nanoparticles - Effect of Dendritic Structure on Nanoparticle Size and Chemical Stability
J. Coll. Interface Sci. 2006, 302, 178-186.
65 M.A. Kostiainen*, G.R. Szilvay, D.K. Smith*, M.B. Linder, O. Ikkala
Multivalent Dendrons for High Affinity Adhesion of Proteins to DNA
Angew. Chem. Int. Ed. 2006, 45, 3538-3542.
This paper was featured in Chemistry World.
For details click here
64 K.S. Winstanley, A.M. Sayer, D.K. Smith*
Anion Binding by Catechols - an NMR, Optical and Electrochemical Study
Org. Biomol. Chem. 2006, 4, 1760-1767.
63

D.K. Smith
Dendritic Supermolecules - Towards Controllable Nanomaterials (Feature Article + Front Cover)
Chem. Commun. 2006, 34-44.

62 J.G. Hardy, M. Kostiainen, D.K. Smith*, N.P. Gabrielson, D.W. Pack
Dendrons with Spermine Surface Groups as Potential Non-Viral Vectors for Use in Gene Therapy
Bioconjugate Chem. 2006, 17, 172-178.
61 D.K. Smith
The Mid-Lecture Break - An Overview and Some New Approaches
J. Chem. Ed., 2006, 83, 1621-1624.
60 C.S. Love, V. Chechik, D.K. Smith*, I. Ashworth, C. Brennan
Robust Gels Created Using a Self-Assembly and Covalent Capture Strategy
Chem. Commun. 2005, 5647-5649.
59 H.F.M. Nelissen, D.K. Smith
Synthetic Phosphate Receptor
UK Patent Filed August 2005, P110446GB.
58 A.R. Hirst, D.K. Smith*, J.P. Harrington
Unique Nanoscale Morphologies Underpinning Gel-Phase Materials
Chem. Eur. J. 2005, 11, 6552-6559.
57

A.R. Hirst, D.K. Smith
Two-Component Gel-Phase Materials - Highly Tunable Self-Assembling Systems (Concept Article)
Chem. Eur. J., 2005, 11, 5496-5508.

56 A.R. Hirst, D.K. Smith*
Dendritic Gels (Review)
Top. Curr. Chem. (Special Issue), 2005, 256, 237-273.
55 B. Huang, A.R. Hirst, D.K. Smith*, V. Castelletto, I.W. Hamley
A Direct Comparison of One- and Two-Component Dendritic Self-Assembled Materials - Elucidating Molecular Recognition Pathways
J. Am. Chem. Soc. 2005, 127, 7130-7139.
54 M.A. Kostiainen, J.G. Hardy, D.K. Smith*
High Affinity Multivalent DNA Binding Using Low Molecular Weight Dendrons
Angew. Chem. Int. Ed., 2005, 44, 2556-2559.
53 B. Wright et al. - we (H.F.M. Neliseen and D.K. Smith) are acknowledged on this paper for the custom synthesis of isotopicaly labelled peptides required for the urinary analysis
Is the Presence of Urinary Indolyl-3-acryloyl glycine Associated with Autism Spectrum Disorder?
Developmental Medicine and Child Neurology, 2005, 47, 190-192.
52 C.S. Love, V. Chechik*, D.K. Smith*, K. Wilson, I. Ashworth, C. Brennan
Synthesis of Gold Nanoparticles Within a Supramolecular Gel-Phase Network
Chem. Commun., 2005, 1971-1973.
51 D.K. Smith*, S.V. Brignell, J.G. Hardy, A.R. Hirst, B. Huang, C.S. Love
Self-Assembly Using Dendritic Building Blocks - Towards Controllable Nanomaterials (Review)
Prog. Poly. Sci. (Special Issue), 2005, 30, 220-293.
This is a major comprehensive review article dealing with this important area of nanofabrication.
In the quarter of its publication it was one of the most highly downloaded articles on the web - reaching number 13 across all chemistry articles published by Elsevier.
50 D.K. Smith*
A Supramolecular Approach to Medicinal Chemistry - Medicine Beyond the Molecule
This paper provides a unique review of medicinal chemistry from the viewpoint of non-covalent interactions and a supramolecular approach.
J. Chem. Ed., 2005, 82, 393-400.
49 J.G. Hardy, A.R. Hirst, D.K. Smith*, I. Ashworth, C. Brennan
Controlling the Materials Properties and Nanostructure of a Single-Component Dendritic Gel by Adding a Second Component
Chem. Commun. 2005, 385-387.
48 Editorial
RSC Higher Education Teaching Award Prize Winners 2004
Education in Chemistry, 2004, 41, 116.
47 A.R. Hirst, D.K. Smith*
Self-Assembly of Two Component Peptidic Dendrimers: Dendritic Effects on Materials Properties
Org. Biomol. Chem., 2004, 2, 2965-2971.
46 A.R. Hirst, D.K. Smith*
Solvent Effects on Supramolecular Gel-Phase Materials: Two-Component Dendritic Gel
Langmuir, 2004, 20, 10851-10857.
45 C.S. Love, A.R. Hirst, V. Chechik, D.K. Smith*, I. Ashworth, C. Brennan
One Component Gel Based on Peptidic Dendrimers: Dendritic Effects on Materials Properties
Langmuir, 2004, 20, 6580-6585.
44

A.R. Hirst, D.K. Smith*, M.C. Feiters, H.P.M. Geurts
Two Component Dendritic Gel: Effect of Stereochemistry on the Supramolecular Chiral Assembly
Chem. Eur. J. 2004, 10, 5901-5910.
This paper was awarded VIP status by the referees.

43 A.R. Hirst, D.K. Smith*, M.C. Feiters, H.P.M. Geurts
Two Component Dendritic Gel: Effect of Spacer Chain Length on the Supramolecular Chiral Assembly
Langmuir, 2004, 20, 7070-7077.
42 D.L. Stone, D.K. Smith*, A.C. Whitwood
Copper Amino-Acid Complexes with Encapsulated Metal Centres
Polyhedron, 2004, 23, 1709-1717.
41 G.M. Dykes, D.K. Smith*, A. Caragheoropol
NMR and ESR Investigations of the Interaction Between a Carboxylic Acid and an Amine at the Focal Point of L-Lysine Based Dendritic Branches
Org. Biomol. Chem., 2004, 2, 922-926.
40 C.S. Love, V. Chechik*, D.K. Smith*, C. Brennan
Dendron-Stabilised Gold Nanoparticles: Generation Dependence of Core Size and Thermal Stability
J. Mater. Chem., 2004, 14, 919-923.
39 D.K. Smith*
Chiral Dendrimers with Biomedical Applications
Speciality Chemicals Magazine, 2004, Vol 24, No. 1 (Dec./Jan.) pp 42-43.
38 D.K. Smith*
Molecular Recognition Using Dendritic Building Blocks
Polymer Preprints (ACS Meeting, New York), 2003, 44, 487-488.
37 D.K. Smith*
Rapid NMR Screening of Chloride Receptors: Uncovering Catechol as a Useful Anion Binding Motif
Org. Biomol. Chem., 2003, 1, 3874-3877.
36 D.L. Stone, G.M. Dykes, D.K. Smith*
Dendritic Lanthanide Complexes: The Effect of Lewis Acid Encapsulation
Dalton Trans., 2003, 3902-3906.
35 A.R. Hirst, D.K. Smith*, M.C. Feiters, H.P.M. Geurts, A.C. Wright
Two Component Dendritic Gels: Easily Tunable Materials
J. Am. Chem. Soc., 2003, 125, 9010-9011.
34 M. Driffield, D.K. Smith*, A.S. Prangle, D.M. Goodall
Convergent and Divergent Syntheses of Dendritic branches based on L-lysine: Is the Stereochemistry Preserved Throughout the Synthesis?
Org. Biomol. Chem., 2003, 1, 2612-2620.
33 D.K. Smith*
Sense and Sensor Ability
Chemistry Review, 2003, 13, November, 2-5
32 D.K. Smith*
To Molecules and Beyond
Education in Chemistry, 2003, 40, 67-69 and 77
31 G.M. Dykes, D.K. Smith*
Supramolecular Dendrimer Chemistry: Using Dendritic Crown Ethers to Reversibly Generate Functional Assemblies
Tetrahedron,2003, 59, 3999-4009 (special issue on dendrimer chemistry).
30 D.K. Smith*
Editorial - Recent Developments in Dendrimer Chemistry
Tetrahedron - special issue, 2003, 59, 3797-3798.
29 D.L. Stone, D.K. Smith*
Anion Binding at the Core of Dendritic Ferrocene Derivatives
Polyhedron, 2003, 22, 763-768 (part of a special issue on supramolecular chemistry).
28 R.E. Heath, G.M. Dykes, H. Fish, D.K. Smith*
Rapid Screening of Binding Constants by Calibrated Competitive 1H NMR
Chem. Eur. J., 2003, 9, 850-855.
27 M. Driffield, D.M. Goodall, A.S. Klute, D.K. Smith*, K. Wilson
Synthesis and Characterisation of Silica-Supported L-Lysine Based Dendritic Branches
Langmuir, 2002, 18, 8660-8665.
26 G.M. Dykes, D.K. Smith*, G.J. Seeley,
Controlled Release of a Dendritically Encapsulated Template Molecule
Angew. Chem. Int. Ed., 2002, 41, 3254-3257.
25 D.L. Stone, D.K. Smith*, P.T. McGrail,
Ferrocene Encapsulated within Symmetric Dendrimers: A Deeper Understanding of Dendritic Effects on Redox Potential
J. Am. Chem. Soc., 2002, 124, 856-864
24 G.M. Dykes, L.J. Brierley, D.K. Smith*, P.T. McGrail,
Supramolecular Solubilisation of Hydrophilic Dyes Using Individual Dendritic Branches
Chem. Eur. J., 2001, 7, 4730-4739.
23 M. Driffield, E.T. Bergstrom, D.M. Goodall*, A.S. Prangle, D.K. Smith,
High Performance Liquid Chromatography Applications of OR Detection with Compensation for Scattering and Absorbance at the Laser Wavelength
J. Chromatography A, 2001, 939, 41-48.
22 A.V. Davis, M. Driffield, D.K. Smith*,
A Dendritic Active Site: Diastereoselctive Catalysis of the Nitroaldol Reaction
Org. Lett., 2001, 3, 3075-3078.
21 D.K. Smith*
New Dawn For Chemistry
Chemistry and Industry, 2001, 16 April, 247-248. (Essay Style Book Review)
20 K.S. Partridge, D.K. Smith*, G.M. Dykes, P.T. McGrail,
Supramolecular Two-Component Dendritic Gel,
Chem. Commun., 2001, 319-320.
An overview of this paper was published as a 'highlight': Chemistry and Industry, 2001, April 2, 219.
19 S. Koenig, L. Müller, D.K. Smith*,
Dendritic Biomimicry: Microenvironmental Hydrogen Bonding Effects on Tryptophan Fluorescence
Chem. Eur. J., 2001, 7, 979-986.
18 D.K. Smith, F. Diederich,
Supramolecular Dendrimer Chemistry: A Journey through the Branched Architecture,
Top. Curr. Chem., 2000, 210, 183-227. (Review)
17 D.K. Smith*, L. Müller,
Dendritic Biomimicry: Microenvironmental Effects on Tryptophan Fluorescence,
Chem. Commun., 1999, 1915-1916.
16 D.K. Smith*,
Supramolecular Dendritic Solubilisation of a Hydrophilic Dye and Tuning of its Optical Properties,
Chem. Commun., 1999, 1685-1686.
For a review of this paper see: Chemistry in Britain, 1999, November, page 20.
15 D.K. Smith*,
Branched Ferrocene Derivatives: Using Redox Potential to Probe the Dendritic Interior,
J. Chem. Soc. Perkin Trans. 2, 1999, 1563-1565.
14 D.K. Smith, A. Zingg, F. Diederich*,
Dendroclefts: Optically Active Dendritic Receptors for the Selective Recognition and Chiroptical Sensing of Monosaccharide Guests,
Helv. Chim. Acta, 1999, 82, 1225-1241.
13 J.M. Lloris, R. Martinez-Manez*, M.E. Padilla-Tosta, T. Pardo, J. Soto, P.D. Beer*, J. Cadman, D.K. Smith,
Cyclic and Open Chain Aza-Oxa Ferrocene-Functionalised Derivatives as Receptors for the Electrochemical Sensing of Toxic Heavy Metal Ions in Aqueous Environments,
J. Chem. Soc., Dalton Trans., 1999, 2359-2369.
12

P.D. Beer, P.A. Gale, D.K. Smith,
Supramolecular Chemistry, Oxford University Press, Primer Text, Oxford, 1999.
Buy this at Amazon
11 P.D. Beer*, J. Cadman, J.M. Lloris, R. Martinez-Manez*, M.E. Padilla, T. Pardo, D.K. Smith, J. Soto,
Selective Electrochemical Recognition of Sulfate over Phosphate and Phosphate over Sulphate using Polyaza Ferrocene Macrocyclic Receptors in Aqueous Solution,
J. Chem. Soc. Dalton Trans., 1999, 127-133.
10 D.K. Smith, F. Diederich, A. Zingg,
Supramolecular Dendrimer Chemistry: Molecular Recognition within the Dendritic Environment,
in: Supramolecular Science: Where it is and where it is going, pp 261-272, NATO ASI Series Book, Kluwer Academic Press, Dordrecht, 1999.
9 D.K. Smith, F. Diederich*,
Dendritic Hydrogen Bonding Receptors: Enantiomerically Pure Dendroclefts for the Selective Recognition of Monosaccharides,
Chem. Commun., 1998, 2501-2502.
8 D.K. Smith, F. Diederich*,
Functional Dendrimers: Unique Biological Mimics,
Chem. Eur. J., 1998, 4, 1353-1361. (Review)
This paper has now been cited over 250 times, making it the most highly cited Concept Article ever published in Chem. Eur. J. - for details click here.
7 P.D. Beer*, D.K. Smith,
Tunable Bis(ferrocenyl) Receptors for the Solution Phase Electrochemical Sensing of Transition-Metal Cations,
J. Chem. Soc. Dalton Trans., 1998, 417-423.
6 P.D. Beer*, A.R. Graydon, A.O.M. Johnson, D.K. Smith*,
Neutral Ferrocenoyl Receptors for the Selective Recognition and Sensing of Anionic Guests,
Inorg. Chem., 1997, 36, 2112-2118.
5 P.D. Beer, D.K. Smith,
Anion Binding and Recognition by Inorganic Based Receptors,
Prog. Inorg. Chem., 1997, 46, 1-96. (Review)
4 P.D. Beer*, M.G.B. Drew, D.K. Smith,
Selective Electrochemical Recognition of Bidentate Anionic Guests in Competitive Solvents using Novel Ferrocenyl Thiourea and Guanidinium Receptors,
J. Organomet. Chem., 1997, 543, 259-261.
3 P.D. Beer*, Z. Chen, M.G.B. Drew, A.O.M. Johnson, D.K. Smith, P. Spencer,
Transition Metal Cation and Phosphate Anion Electrochemical Recognition in Water by New Polyaza Ferrocene Macrocyclic Ligands,
Inorg. Chim. Acta, 1996, 246, 143-150.
2 P.D. Beer*, D. Hesek, J.E. Kingston, D.K. Smith, S.E. Stokes, M.G.B. Drew,
Anion Recognition by Redox Responsive Ditopic Bis-Cobaltocenium Receptor Molecules Including a Novel Calix[4]arene Derivative that Binds a Dicarboxylate Dianion,
Organometallics, 1995, 14, 3288-3295.
1 P.D. Beer*, M.G.B. Drew, A.R. Graydon, D.K. Smith, S.E. Stokes,
Quantitative and Structural Investigations of Hydrogen-bonding Interactions in Anion Binding of Mono- and 1,1'-Bis-substituted Aryl Cobaltocenium Receptors,
J. Chem. Soc. Dalton Trans., 1995, 403-408.