Exercise: Prophylactic administration of parenteral steroids, answer 5

Question 5: In Figure 1, is there evidence of statistical heterogeneity?

Suggested answer:

Yes, there is evidence of statistical heterogeneity.

Two pairs of confidence intervals do not overlap (for Francois and Darmon and for Francois and Gaussorges). The test for heterogenity has chi-squared = 19.48, P<0.002, which is highly significant. Hence there is a lot of evidence of statistical heterogeneity.

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