Exercise: Endarterectomy versus stenting using CMA2, answer 12

Question 12: What method could we use to examine the effect of calendar time on treatment effect?

Suggested answer:

We want to see whether the treatment effect is related to calendar time, which can be represented by the year of pubication. This can be done by regression of the effect on year, weighted for the amount of information in the usual meta-analysis way. This is often called meta-regression.

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